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Retatrutide 20mg (R&D Only)
£145
Retatrutide 20mg is a high-quality research peptide developed for laboratory studies focused on metabolic activity, appetite regulation, and weight-related pathways. Intended for research and development use only.
Retatrutide 20mg (R&D Only)
Retatrutide 20mg Only” is an unapproved, research-grade peptide (triple agonist: GLP-1/GIP/glucagon) sold by labs like Limitless Biotech, Peptide Sciences, or Chinese suppliers (e.g., via Telegram/AliExpress). Labeled “not for human use” to skirt regulations, but widely used off-label for weight loss. Not from Eli Lilly trials (max 12mg); 20mg is 1.7x trial max.
Key Facts
| Aspect | Details |
|---|---|
| Status | Investigational only**. Phase 3 trials ongoing (approval ~2026+). No FDA approval. |
| Form | 20mg lyophilized vial (99%+ claimed purity). Reconstitute with bacteriostatic water; weekly subQ injection (e.g., 2-4mg doses from vial). |
| Source/Purity | “R&D” labs claim HPLC/MS-tested (95-99%). Real-world tests (Janoshik, Reddit): 85-98% pure; frequent impurities (e.g., glucagon fragments). |
| Cost | $200-400/vial (5-10 weeks at 2-4mg/week). |
Evidence & Performance
- Official Trials (Phase 2, NEJM 2023): 12mg weekly = 24% weight loss (48 weeks), -2.0% HbA1c. Superior to tirzepatide in glucagon-driven fat burn/muscle preservation.
- 20mg User Data (Anecdotal, n=thousands on r/Retatrutide, GLP1s):
| Dose | Avg. Loss (4-12wks) | Common Sides |
|---|---|---|
| 4-8mg | 15-25lbs/mo | Mild nausea (60%) |
| 12-20mg | 25-40lbs/mo (early) | Severe GI (80%), HR+20bpm, fatigue |
Risks (Elevated at 20mg)
| Risk Category | Specifics | Supporting Data |
|---|---|---|
| GI/Acute | Vomiting, cramps, dehydration (dose-proportional). | 70% incidence >12mg in trials. |
| Cardiac | Tachycardia (glucagon effect); AFib risk. | Phase 2: +10-15bpm; case reports at high doses. |
| Long-Term | Pancreatitis, thyroid tumors, gastroparesis. | Rodent data; similar to GLP-1 class (FDA warnings). |
| Product | Bacterial contamination, underdosing (20-30% fakes). | FDA 2024 peptide seizures. |
Bottom Line: High-risk, unproven. 20mg exceeds safe data; expect amplified sides with questionable purity. Skip it—wait for approval or use FDA-approved tirzepatide/semaglutide (proven 15-20% loss). If experimenting, start <2mg/week under medical supervision, monitor HR/bloodwork. Source from tested vendors (e.g., with CoAs), but liability is yours. Clinicaltrials.gov for legit access. Stop if HR>100bpm or persistent vomiting.
1 review for Retatrutide 20mg (R&D Only)
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United Kingdom:
Estimated delivery within 1–3 working days after dispatch
Europe:
Estimated delivery within 3–7 working days
International Orders:
Estimated delivery within 5–10 working days, depending on the destination
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Connor Legge –
Early days but I can already see positive changes. It’s helped with controlling cravings and keeping my eating habits more structured.